{"id":541,"date":"2018-09-12T09:00:00","date_gmt":"2018-09-12T09:00:00","guid":{"rendered":"https:\/\/isosolution-v2.staging.xiyx.ai\/news\/first-in-human-study-of-177lu-eb-psma-617-in-patients-with-metastatic-castration-resistant-prostate-cancer\/"},"modified":"2018-09-12T09:00:00","modified_gmt":"2018-09-12T09:00:00","slug":"first-in-human-study-of-177lu-eb-psma-617-in-patients-with-metastatic-castration-resistant-prostate-cancer","status":"publish","type":"iso_news","link":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/news\/first-in-human-study-of-177lu-eb-psma-617-in-patients-with-metastatic-castration-resistant-prostate-cancer\/","title":{"rendered":"Premi\u00e8re \u00e9tude sur 177Lu-EB-PSMA-617 chez des patients pr\u00e9sentant un cancer de la prostate r\u00e9sistant \u00e0 la castration m\u00e9tastatique"},"content":{"rendered":"<p>Cette premi\u00e8re \u00e9tude chez l'homme a d\u00e9montr\u00e9 que 177Lu-EB-PSMA-617 avait une accumulation plus \u00e9lev\u00e9e de mCRPC et que la faible dose d'imagerie semble efficace dans le traitement des tumeurs avec des absorptions \u00e9lev\u00e9es de 68Ga-PSMA-617. Des absorptions \u00e9lev\u00e9es de 177Lu-EBPSMA-617 dans les reins et la moelle osseuse rouge ont \u00e9t\u00e9 bien tol\u00e9r\u00e9es \u00e0 la faible dose administr\u00e9e. D'autres \u00e9tudes avec une augmentation de la dose et de la fr\u00e9quence d'administration sont justifi\u00e9es. <a href=\"https:\/\/isosolutions.com\/first-in-human-study-of-177lu-eb-psma-617-in-patients-with-metastatic-castration-resistant-prostate-cancer\/\"><span aria-label=\"Continuer la lecture Premi\u00e8re \u00e9tude sur 177Lu-EB-PSMA-617 chez des patients pr\u00e9sentant un cancer de la prostate r\u00e9sistant \u00e0 la castration m\u00e9tastatique\">(plus...)<\/span><\/a><\/p>\n<\/p><\/div>\n<p>\u00c9tiquettes : <a href=\"https:\/\/isosolutions.com\/news-tag\/isosolutions\/\" rel=\"tag\">isoSolutions<\/a> <a href=\"https:\/\/isosolutions.com\/news-tag\/lu-177\/\" rel=\"tag\">Lu-177<\/a> <a href=\"https:\/\/isosolutions.com\/news-tag\/radiochemicals\/\" rel=\"tag\">Produits radiochimiques<\/a> <a href=\"https:\/\/isosolutions.com\/news-tag\/research\/\" rel=\"tag\">Recherche<\/a><\/p>\n<\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>This first-in-human study demonstrated that 177Lu-EB-PSMA-617 had higher accumulation in mCRPC and that low imaging dose appears to be effective in treating tumors with high 68Ga-PSMA-617 uptakes.\u2026<\/p>","protected":false},"featured_media":567,"template":"","iso_news_section":[43],"class_list":["post-541","iso_news","type-iso_news","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/iso_news\/541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/iso_news"}],"about":[{"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/types\/iso_news"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/media\/567"}],"wp:attachment":[{"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/media?parent=541"}],"wp:term":[{"taxonomy":"iso_news_section","embeddable":true,"href":"https:\/\/isosolution-v2.staging.xiyx.ai\/fr\/wp-json\/wp\/v2\/iso_news_section?post=541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}